BT is a 47-year-old man admitted to the hospital with prostatic hyperplasia requiring transurethral resection of the prostate (TURP). The procedure is completed without complication and BT returns to the ward with an indwelling catheter in place. It remains in situ for three daysAfter the catheter is removed, BT experiences urinary frequency and a burning sensation during micturition. A urine sample is taken and sent to the microbiology laboratory for analysis. The microbiology report shows the following:Microscopy: white blood cells ++; Gram-positive rodsCulture: Pseudomonas aerginosaSensitivity: amoxicillin: resistant; cephalexin: sensitive; trimethoprim: resistant; gentamicin: sensitiveQuestions:Briefly explain the TURP procedure and what it is meant to do.Why was BT susceptible to a UTI?Which antibacterial agent(s) would be effective in the therapy of BT’s urinary tract infection?State the general mechanisms of action of each of the four antibacterial agents.
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